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Advanced Staining: art or science?

For an optimal-only result

The complexities of Advanced Staining

Advanced Staining is becoming increasingly complex. The growing demand for Diagnostic precision has nurtured the need for quality staining – all this on top of the ever-increasing number of cancer cases, stricter government regulations, and pathology staff shortages.

To overcome these challenges, the industry adapted and spawned numerous variables and possibilities, offering significant flexibility, and leading to a lot of subjectivity in order to achieve the correct staining.

Diagnostic confidence starts with slide quality - yet studies have shown that one in five IHC slides may be insufficient for diagnosis.

Advanced Staining: Art or science?

For years, achieving the "right" stain often depended on local optimisation, protocol adjustments and individual expertise. Different laboratories frequently developed their own approaches to reach acceptable results. But when diagnostic decisions depend on detecting clinically relevant biomarkers—including difficult low-positive cases—subjectivity introduces risk. The question is no longer how a stain looks. The question is whether the stain delivers the diagnostic confidence pathologists need to make the right decision, every time.

Back to the diagnostic essence of IHC

In modern pathology, the question is no longer whether a stain looks good. The real purpose of IHC is to reveal diagnostically relevant information with the sensitivity and consistency needed for confident clinical decisions. Every missed low-positive case can impact diagnosis, treatment selection, and patient outcomes. At Sakura, we believe pathology should not rely on constant optimisation, subjective adjustments, or individual interpretation of protocols. Every assay should perform as intended, every time.

That is why we developed our Optimal Only philosophy: a fully validated approach in which antibodies, protocols, detection systems and instrumentation work together as one integrated solution, delivering diagnostic confidence from day one. Optimal Only. Because diagnostic certainty starts with the stain.

Advanced Staining with Sakura is your source for:

  • confidence in every slide to make the right diagnosis

  • a solution where you can load any slide, any biomarker, at any time on any station

  • predictable case turnaround time

  • digital support through GenieOnline

  • control of your daily workflow

  • IVDR readiness

  •  control of your inventory management

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Introducing our next-generation advanced staining system

Discover how Tissue-Tek Genie can provide optimal slides with the same turnaround time, using a standard protocol.

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IVDR

Comply with new regulations keeping patients in focus.

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